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and decreased mRNA expression of proinflammatory cytokines IL-1, IL-6, and TNF, suppressed NF-B activation, and inhibited the stressed-induced NLRP3 inflammasome axis activation, along with reducing the transformation of pro-IL-1 into mature IL-1

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Except for the Sham group, which received intraperitoneal injections of physiological saline, the remaining five groups were administered daily intraperitoneal injections of 5 mg/kg testosterone propionate